Prof. Dr. Tim Liedl

Tim Liedl is Professor for experimental physics at the Ludwig-Maximilians Universität since 2009.
He received his diploma in physics in 2004 in the group of Wolfgang J. Parak at Ludwig-Maximlians-University Munich (LMU) where he worked on the development of hydrophilic coatings for fluorescent semiconductor nanoparticles. In 2007 he obtained his Ph.D. in the group of Friedrich C. Simmel studying DNA-based nanodevices and switches which are driven by chemical oscillations. From spring 2007 till summer 2009 he visited William M. Shih's laboratory at Dana-Farber Cancer Institute / Harvard Medical School where he used the DNA-origami method to construct self-assembling two- and three-dimensional structures.
The research of Tim Liedl is multi-disciplinary and exploratory positioned at the interface between nanoscience, synthetic biology and cell-biology. Its current focus lies on the application of DNA-based nanostructures in biology and on self-assembled plasmonic materials.

Selected publications

P. C. Nickels, B. Wünsch, P. Holzmeister, W. Bae, L. M. Kneer, D. Grohmann, P. Tinnefeld, T. Liedl
Molecular force spectroscopy with a DNA origami–based nanoscopic force clamp
Science 354, 6310, pp. 305-307 (2016)

R. Schreiber, J. Do, E. Roller, T. Zhang, V. J. Schüller, P. C. Nickels, J. Feldmann, T. Liedl
"Hierarchical Assembly of Metal Nanoparticles, Quantum Dots and Organic Dyes Using DNA Origami Scaffolds"
Nature Nanotechnology 9, 74-78 (2014)

A. Kuzyk, R. Schreiber, Z. Fan, G. Pardatscher, E. Roller, A. Högele, F. C. Simmel, A. O. Govorov, T. Liedl
DNA-based self-assembly of chiral plasmonic nanostructures with tailored optical response
Nature 483, 311-314 (2012)

T. Liedl, B. Högberg, J. Tytell, D. E. Ingber, and W. M. Shih
Self-assembly of 3D prestressed tensegrity structures from DNA
Nature Nanotechnology 5, 520–524 (2010)

S. M. Douglas, H. Dietz, T. Liedl, B. Högberg, F. Graf, and W. M. Shih
Self-assembly of DNA into nanoscale three-dimensional shapes
Nature 459, 414–418 (2009)

S.K. Kufer, E. Puchner, H. Gumpp, T. Liedl, and H.E. Gaub
Single-Molecule Cut-and-Paste Surface Assembly
Science 319, 594-496 (2008)

T. Liedl and F. C. Simmel
Switching the conformation of a DNA molecule with a chemical oscillator
Nano Letters 5, 1894-1898 (2005)

C. Kirchner, T. Liedl, S. Kudera, T. Pellegrino, A. M. Javier, H. E. Gaub, S. Stolzle, N. Fertig and W. J. Parak
Cytotoxicity of colloidal CdSe and CdSe/ZnS nanoparticles
Nano Letters 5, 331-338 (2005)

Full list of publications